Segments involving drugs and/or drug use.
- King of the Beach
- Rachael Leigh Cook PSA
- Teletubby Smokes
- Stix are Intended for Children
- Unsolved Case Files: Claus & Effect
- Toy Story 4
- Bert's New Roommate
- Where Do They Get the Energy?
- Perfect Little Girls Who Flip The F&%$ Out
- What, What!
- Behind the Music: Electric Mayhem - Animal is euthanized via lethal injection, Zoot is picked up in Tokyo with thirty seven pounds of hash in his bag.
- Hollywood Spotlight - Hulk snorts cocaine with Bill Bixby, and again later with Ang Lee.
- Meteorgeddon - Steven Tyler proclaims that he just shot smack into both of his eyeballs.
- Beginning Season Five - In the special intro, the narrator says he spent his paycheck on meth (as did Matt and Seth).
- Appeasing the God - One of the teenagers killed uses a bong.